Interaction of Candida albicans Biofilms with Antifungals: Transcriptional Response and Binding of Antifungals to Beta-Glucans
نویسندگان
چکیده
منابع مشابه
Commercial mouthwashes are more effective than azole antifungals against Candida albicans biofilms in vitro.
OBJECTIVE The aim of this study was to evaluate and compare the activity of prescription and over-the-counter antimicrobial compounds against planktonic and biofilm forms of Candida albicans isolated from cases of oral candidiasis in vitro. STUDY DESIGN The efficacy of azoles, polyenes, an echinocandin, and 4 over-the-counter mouthwashes were tested against C. albicans-derived planktonic and ...
متن کاملMultilaboratory testing of two-drug combinations of antifungals against Candida albicans, Candida glabrata, and Candida parapsilosis.
There are few multilaboratory studies of antifungal combination testing to suggest a format for use in clinical laboratories. In the present study, eight laboratories tested quality control (QC) strain Candida parapsilosis ATCC 22019 and clinical isolates Candida albicans 20533.043, C. albicans 20464.007, Candida glabrata 20205.075, and C. parapsilosis 20580.070. The clinical isolates had relat...
متن کاملCytochrome P - 450 - dependent I 4 a - sterol demethylase of Candida albicans and its interaction with mole antifungals
14. 15. Canonica, I+ Fiecchi, A., Galli Kienle, M., Scala, A., Galli, G., Grossi Paoletti, E. & Paoletti, R. (1968) J. Am. Chem. SOC. 90,3597-3598 Yoshida. Y. & Aoyama. Y. (1900) Chirality, 2, 10-15 Yoshida. Y.. Aoyama, Y.. Takano. H. & Kato, T. (1980) Hiochem. Hiophys. Kes. Commun. 137. 5 13-5 10 16. Anderson, N. H., Branch, S. K., Thomas Loefier, R. S., Mann, H. E., Nowell, 1. W. & Walker, 1'...
متن کاملProfile susceptibility to fluconazole and voriconazole antifungals by species of Candida albicans isolated from urine culture
Background The term candiduria can be defined as the observation of yeasts on direct examination of urine through the presence of pseudo-hyphae and fungal growth in urine culture [1]. The yeast Candiduria can be detected in the urine in patients who have bladder colonization and in patients who have urinary tract infection [2]. Currently, there are few options in the medicine antifungal market ...
متن کاملChromosome 5 monosomy of Candida albicans controls susceptibility to various toxic agents, including major antifungals.
Candida albicans is a prevailing fungal pathogen with a diploid genome that can adapt to environmental stresses by losing or gaining an entire chromosome or a large portion of a chromosome. We have previously found that the loss of one copy of chromosome 5 (Ch5) allows for adaptation to the toxic sugar l-sorbose. l-Sorbose is similar to caspofungin and other antifungals from the echinocandins c...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2010
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01638-09